La Liga leaders Barcelona suffered third league defeat of the season as they were stunned by Levante who came from behind to svore three goals in seven second-half minutes.
Lionel Messi had put the champions ahead with a 38th-minute penalty following Jorge Miramon’s foul on Nelson Semedo.
Jose Campana levelled for Levante after 60 minutes, before Borja Mayoral completed the turnaround two minutes later and Nemanja Radoja added a third.
The video assistant referee then denied Messi as his side failed to respond.
The Argentine appeared to have scored an excellent solo goal after a determined run, but Antoine Griezmann had strayed offside in the build-up.
However the result did not change the top position of Ernesto Valverde’s side as closest rivals Real Madrid failed to capitalise the chance as they were held to a goalless draw at home by Real Betis.